Meaning : Work doggedly or persistently.
Example :
She keeps plugging away at her dissertation.
Synonyms : keep one's shoulder to the wheel, peg away, plug away, slog
Keep one's nose to the grindstone ka meaning, vilom shabd, paryayvachi aur samanarthi shabd in Marathi. Keep one's nose to the grindstone ka matlab kya hota hai?