Example : A...youth with a gorgeous red necktie all awry.
His wig was, as the British say, skew-whiff.

Synonyms : askew, cockeyed, lopsided, skew-whiff, wonky

Example : Something is amiss.
Has gone completely haywire.
Something is wrong with the engine.

Synonyms : amiss, haywire, wrong

Example : Something has gone awry in our plans.
Something went badly amiss in the preparations.

Synonyms : amiss

Example : Rugs lying askew.
With his necktie twisted awry.

Synonyms : askew, skew-whiff